• Home
  • Journals
  • For Authors
    • Why Publish With Us
    • Manuscript Preparation
    • Similarity Index
    • Article Processing Charge
    • Downloads
    • Help Center
  • Review and Editorial
    • Review Policy
    • Editorial Policy
    • Terms and Conditions
  • Archives
    • JBAR Archive
    • JSTEI Archive
    • IJBMSR Archive
    • JMSMR Archive
    • BBC Archive
    • AJCSP Archive
    • IJFEE Archive
    • JFLVS Archive
    • IJMP Archive
  • Contact Us
JOURNAL BINET
  • Home
  • Journals
  • For Authors
    • Why Publish With Us
    • Manuscript Preparation
    • Similarity Index
    • Article Processing Charge
    • Downloads
    • Help Center
  • Review and Editorial
    • Review Policy
    • Editorial Policy
    • Terms and Conditions
  • Archives
    • JBAR Archive
    • JSTEI Archive
    • IJBMSR Archive
    • JMSMR Archive
    • BBC Archive
    • AJCSP Archive
    • IJFEE Archive
    • JFLVS Archive
    • IJMP Archive
  • Contact Us
​You are here: Home>JBAR Journal>JBAR-Volume-06>jbar-050215-59.html

Journal of Bioscience and Agriculture Research 


Research article: 
Calcium carbonate supplementation causes preventive approach to toxic effects of mercuric chloride on metabolic regulation in liver of C. punctata
 
Md. Shahidul Haque (a), Md. Mahmudul Hasan (a) and Md. Mosharrof Hossain (b)
 
(a) Dept. of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh
(b) Dept. of Zoology, University of Rajshahi, Rajshahi-6205, Bangladesh


J. bios. agric. res., volume 06, issue 01, pp. 489-500 | Available online: 22 October 2015
DOI: 
http://dx.doi.org/10.18801/jbar.060115.59
calcium_carbonate........................to_toxic_effects_of_mercuric_chloride_on_metabolic_regulation_in_liver_of_c._punctata__v1.1_.pdf
File Size: 618 kb
File Type: pdf
Download File



  • Abstract
  • Citations
  • References
<
>
Abstract: Mercury (Hg) shows the toxic effects in the environment although the etiology is not well characterized and the prevention of toxic effects induced by Hg is an important aspect of metabolic regulation in organisms.  Channa punctata, a variety of species of fish was used in this study and the role of calcium carbonate on cholesterol, triglyceride and protein level in liver induced by HgCl2 was adopted.  Fish were exposed to 1 and 10 µM of HgCl2 for 1h and cholesterol and triglyceride levels in excised liver were enhanced in response to HgCl2 when compared to respective controls however the effects were more pronounced for 1 µM concentration.  Similar stimulatory effects on protein contents were demonstrated whenever they were exposed to HgCl2 (1 and 10 µM) and higher proteins were recorded for 10 µM concentration.  The results indicate that HgCl2 causes severe toxic effects enhancing the above parameters.  To clarify the role of CaCO3 on prevention of these effects, fish were treated with different concentrations (100 µM and 1 mM) of CaCO3 and CaCO3 + HgCl2.  Cholesterol and triglyceride in liver were effectively reduced with CaCO3 (1 mM) + HgCl2 (10 µM) and CaCO3 (100 µM) + HgCl2 (1 µM) while 100 µM of CaCO3 potentially reduced the effects of HgCl2. Although CaCO3 was shown to reduce protein content effectively, however 100 µM concentrations have been found to inhibit the effects of HgCl2 preferentially.  Our findings suggest that calcium carbonate might be involved in prevention of the toxic effects of Hg and may contribute to the survival process of this species.
Key words: Channa punctate, toxic effects, liver, metabolic regulation and mercuric chloride
APA (American Psychological Association)
Haque, M. S., Hasan, M. M. & Hossain, M. M. (2015). Calcium carbonate supplementation causes preventive approach to toxic effects of mercuric chloride on metabolic regulation in liver of C. punctata. Journal of Bioscience and Agriculture Research, 06 (01), 489-500.
 
MLA (Modern Language Association) 
Haque, M. S., Hasan, M. M. & Hossain, M. M. “Calcium carbonate supplementation causes preventive approach to toxic effects of mercuric chloride on metabolic regulation in liver of C. punctata.” Journal of Bioscience and Agriculture Research, 06.01 (2015): 489-500.
 
Chicago/Turabian
Haque, M. S., Hasan, M. M. & Hossain, M. M.  “Calcium carbonate supplementation causes preventive approach to toxic effects of mercuric chloride on metabolic regulation in liver of C. punctata.” Journal of Bioscience and Agriculture Research, 06, no. 01 (2015): 489-500.
  1. ​Al-Whaibi, M. H. (2011). Plant heat-shock proteins: A mini review. Journal of King Saud University - Science, 23(2), 139-150.
  2. Ahmad, I., Maria, V. L., Oliveira, M., Pacheco, M. & Santos, M. A. (2006).. Oxidative stress and genotoxic effects in gill and kidney of Anguilla anguilla L. exposed to chromium with or without preexposure to b-naphthoflavone. Mutation Research, 608, 16-28.​ http://dx.doi.org/10.1016/j.mrgentox.2006.04.020
  3. Alvarez, M. D., Murphy, C. A., Rose, K. A., McCarthy, I. D. & Fuiman, L. A. (2006). Maternal body burdens of methylmercury impair survival skills of offspring in Atlantic croaker (Micropogonias undulatus). Aquatic Toxicology, 80, 329-337.​ http://dx.doi.org/10.1016/j.aquatox.2006.09.010
  4. Bainy, A. C. D. (1996). Oxidative stress as biomarker of polluted aquatic sites. In: Val AL, Almeida-Val VMF, Randall DJ (eds) Physiology and Biochemistry of the fishes of the Amazon. INPA, Manaus, pp. 101-110.
  5. Black, F. J., Bruland, K. W., Flegal, A. R. (2007). Competing ligand exchangesolid phase extraction method for the determination of the complexation of dissolved inorganic mercury (II) in natural waters. Analytica Chimica Acta, 598, 318-333.​ http://dx.doi.org/10.1016/j.aca.2007.07.043
  6. Banerjee, B. D., Seth, V., Bhattacharya, A., Pasha, S. T. & Chakraborty, A. K. (1999). Biochemical effects of some pesticides on lipid peroxidation and free-radical scavengers. Toxicology Letters, 107, 33-47.
  7. Chen, C. Y., Dionne, M., Mayes, B. M., Ward, D. M., Sturup, S. & Jackson, B. P. (2009). Mercury bioavailability and bioaccumulation in estuarine food webs in the Gulf of Maine. Environmental Science & Technology, 43, 1804-1810. http://dx.doi.org/10.1021/es8017122
  8. Carta, P., Flore, C., Alinovi, R., Ibba, A., Tocco, M. G., Aru, G., Carta, R., Girei, E., Mutti, A., Lucchini, R. & Randaccio, F. S. (2003). Sub-clinical neurobehavioral abnormalities associated with low level of mercury exposure through fish consumption. Neurotoxicology, 24, 617-623.​ http://dx.doi.org/10.1016/S0161-813X(03)00080-9
  9. Das, S. C. S. & Datta, S. (2008). Effect of contact time on the acute toxicity of mercury to scale carp. Journal of Indian Fisheries Association, 35, 113-120.
  10. Datta, S., Singh, A. & Das, R. C. (2003).  Influence of soil sediment factors on the acute toxicity of inorganic mercury to Catla catla. Environment and Ecology, 21(3), 542-551.
  11. Elia, A. C., Galarini, R., Taticchi, M. I., Do¨rra, A. J. M. & Mantilacci, L. (2003). Antioxidant responses and bioaccumulation in Ictalurus melas under mercury exposure. Ecotoxicology and Environmental Safety, 55, 162-167. http://dx.doi.org/10.1016/S0147-6513(02)00123-9
  12. Giudetti, A. M., Damiano, F., Gnoni, G. V. & Siculella, L. (2013).  Low level of hydrogen peroxide induces lipid synthesis in BRL-3A cells through a CAP-independent SREBP-1a activation. International Journal of Biochemistry and Cell Biology, 45, 1419-1426.​ http://dx.doi.org/10.1016/j.biocel.2013.04.004
  13. Jackman, A. P., Kennedy, V. C. & Bhatia, N. (2001). Interparticle migration of metal cations in stream sediments as a factor in toxics transport. Journal of Hazardous Materials, 82(1): 27-41.​ http://dx.doi.org/10.1016/S0304-3894(00)00349-6
  14. Kenny, A. P. (1952). The determination of cholesterol by the Liebermann Burchard reaction. Biochemical Journal, 52(4), 611-619. http://dx.doi.org/10.1042/bj0520611
  15. Lowry, O. H., Rosenbrough, N. J. & Randall, R. J. (1951). Protein measurement with the Folin-phenol reagent. Journal of Biological Chemistry, 183, 265-275.
  16. Lopez, P. A., Pinheiro, T., Santos, M. C., Mathias, M. L., Collares-Pereira, M. J. & Viesgas-Crespo, A. M. (2001). Response of antioxidant enzymes in freshwater fish populations (Leucicus alburnoides complex) to inorganic pollutants exposure. Sci. Total Environ., 280, 153-163.
  17. Li, Z. H., Chen, L., Wu, Y. H., Li, P., Li, Y. F. & Ni, Z. H. (2014). Effects of mercury on oxidative stress and gene expression of potential biomarkers in larvae of the Chinese rare minnow Gobiocypris rarus. Arch Environ Contam Toxicology, 67(2), 245-51.​ http://dx.doi.org/10.1007/s00244-014-0034-6
  18. Oliveira Ribeiro, C. A., Gumara˜es, J. R. D. & Pfeiffer, C. (1996). Accumulation and distribution of inorganic mercury in a tropical fish (Trichomycterus zonatus). Ecotoxicology and Environmental Safety, 34, 190-195. http://dx.doi.org/10.1006/eesa.1996.0063
  19. Padmini, E., Hepshibha, B. T. & Shellomith, A. S. S. (2004). Aquaculture, 5(1): 115-118.
  20. Roy, S. K. & Haque, M. S. (2009). Interaction of arsenic on cold-induced adaptive response involving the change of liver weight of fish Channa punctatus. Bangladesh Journal of Medical Science, 15(2), 115-119.
  21. Rothschild, R. F. & Duffy, L. K. (2005). Mercury concentrations in muscle, brain and bone of Western Alaskan waterfowl. Science of the Total Environment, 349: 277-283.​ http://dx.doi.org/10.1016/j.scitotenv.2005.05.021
  22. Rangwala, S. M. & Lazar, M. A. (2000). Transcriptional control of adipogenesis. Annual Review of Nutrition, 20, 535-559. http://dx.doi.org/10.1146/annurev.nutr.20.1.535
  23. Rosen, E. D., Walkey, C. J., Puigserver, P. & Spiegelman, B. M. (2000). Transcriptional regulation of adipogenesis. Genes & Development, 14, 1293-1307.
  24. Risher, J. F. & Amler, S. N. (2005). Mercury exposure: evaluation and intervention the inappropriate use of chelating agents in the diagnosis and treatment of putative mercury poisoning. Neurotoxicology, 26, 691-699. http://dx.doi.org/10.1016/j.neuro.2005.05.004
  25. Shastri, Y. & Diwekar, U. (2008). Optimal control of lake pH for mercury bioaccumulation control. Ecological Modelling, 216, 1-17. http://dx.doi.org/10.1016/j.ecolmodel.2008.03.019
  26. Ung, C. Y., Lam, S. H., Hlaing, M. M., Winata, C. L., Korzh, S., Mathavan, S. & Gong, Z. (2010). Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation.  BMC Genomics, 11, 212. http://dx.doi.org/10.1186/1471-2164-11-212
  27. Verlecar, X. N., Jena, K. B. & Chainy, G. B. N. (2007). Biochemical markers of oxidative stress in Perna viridis exposed to mercury and temperature. Chemico-Biological Interactions, 167, 219-226. http://dx.doi.org/10.1016/j.cbi.2007.01.018
  28. Verlecar, X. N., Jena, K. B. & Chainy, G. B. N. (2008). Modulation of antioxidant defences in digestive gland of Perna viridis (L.), on mercury exposures. Chemosphere, 71, 1977-1985.​ http://dx.doi.org/10.1016/j.chemosphere.2007.12.014
  29. Zhang, L. & Wong, M. H. (2007). Environmental mercury contamination in China: sources and impacts. Environment International, 33, 108-121.​ http://dx.doi.org/10.1016/j.envint.2006.06.022
Open Access | Powered by Scribd
© Haque et al. 2015. This article published by Journal BiNET is freely available for anyone to read, share, download, print, permitted for unrestricted use and build upon, provided that the original author(s) and publisher are given due credit. All Published articles are distributed under the Creative Commons Attribution 4.0 International License.

For Authors

Browse our journals
​
Manuscript preparation
Downloads for authors
Indexing of journals
​Article processing charge
Help center
​Journal blog
Author Login Author Login Hi, (First Name) Member Area | Log Out
Author Login
Welcome, (First Name)!

Forgot? Show
Log In
Enter Member Area
(Message automatically replaces this text)
OK
My Profile Not a member? Sign up. Log Out

Manuscript Submission

Upload Article Here

Join as reviewer & editor

Journal News and updates

  • Number of article published online: 400+
  • 350+ International editorial & review members
  • Google Scholar Citations 1071, h-index 15
  • Index Copernicus Value: ICV 67.42
  • JBAR Volume 25, JSTEI Volume 9, IJBMSR Volume 9, JMSMR Volume 5, AJCSP Volume 3, IJFEE Volume 1 published recently
  • ​Article submissions open for September 2020. 
Copyright: Journal BiNET 2014-2020. All rights reserved. Terms | Privacy | Feedback | Advertise with us | We are hiring !
  • Home
  • Journals
  • For Authors
    • Why Publish With Us
    • Manuscript Preparation
    • Similarity Index
    • Article Processing Charge
    • Downloads
    • Help Center
  • Review and Editorial
    • Review Policy
    • Editorial Policy
    • Terms and Conditions
  • Archives
    • JBAR Archive
    • JSTEI Archive
    • IJBMSR Archive
    • JMSMR Archive
    • BBC Archive
    • AJCSP Archive
    • IJFEE Archive
    • JFLVS Archive
    • IJMP Archive
  • Contact Us