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RESEARCH ARTICLE: 
Antimicrobial sensitivity patterns among sepsis patients in intensive care unit of Dhaka Medical College Hospital, Bangladesh

Ahad Mahmud Khan (1), Fatima Tul Jannat (2) and Md. Faizul Ahasan (3) 
1Projahnmo, Johns Hopkins University, Dhaka, Bangladesh. Phone: +880-2-55035439
2Dept. of Radiology and Imaging, Dhaka Medical College Hospital. Phone: +880-2-55165088
3Occupational Health, Médecins Sans Frontières, Dhaka, Bangladesh. Phone: +880-2-8191519

​J. Mole. Stud. Medici. Res. Volume 02, Issue 01, pp. 80-87 | Available online: 14 April 2017.
Crossref: https://doi.org/10.18801/jmsmr.020117.10

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Title: Antimicrobial sensitivity patterns among sepsis patients in intensive care unit of Dhaka Medical College Hospital, Bangladesh
Abstract:
Background: Sepsis is a leading cause of mortality in Intensive Care Unit (ICU) patients. Rapid initiation of effective empirical therapy lessens both patient mortality rates and time spent in ICU. Objective of the study was to identify microorganisms isolated from sepsis patients in ICU and determine the antimicrobial sensitivity patterns.
Materials and Methods: Hospital based cross-sectional study was conducted among 80 culture positive sepsis patients in the ICU of Dhaka Medical College Hospital (DMCH). 
Results: Most commonly source of isolated organisms were from respiratory (30.0%), genitourinary (23.8%), blood (18.8%) and gastrointestinal (16.3%) sources. Overall gram negative organisms (70.0%) were more common than gram negative organisms (22.5%). The most common organisms in respiratory, genitourinary, gastrointestinal, blood, CSF and pus were Acinatobacter sp. & Streptococcus pneumoniae (25.0%), E. coli (31.6%), E.coli (46.2%), Pseudumonas sp. (60.0%), Neisseria meningitis (60.0%), Staphylococcus aureus (100.0%), respectively. The highest susceptibility was for Colistin (100.0%), Imipenem (73.0%), Moxifloxacin (31.4%) and Piperacillin (68.0%).  Gram negative bacteria were found most sensitive to Colistin (100.0%), Imipenem (82.1%), Moxifloxacin (71.43%), Piperacillin (68.14%) and Amikacin (65.85%) whereas gram positive bacteria to 100% sensitive to Cloxicillin, Azithromicin, Vancomycin and Piperacillin.
Conclusion: Judicious practice of antimicrobial agents for empirical therapy is essential for effective management of sepsis patients in ICU.
Key Words: Antimicrobial sensitivity pattern, Sepsis and ICU

APA (American Psychological Association)
Khan, A. M., Jannat, F. T. and Ahasan, M. F. (2017). Antimicrobial sensitivity patterns among the sepsis patients in the intensive care unit of Dhaka Medical College Hospital, Bangladesh. Journal of Molecular Studies and Medicine Research, 02(01), 80-87.

MLA (Modern Language Association) 
Khan, A. M., Jannat, F. T. and Ahasan, M. F. ''Antimicrobial sensitivity patterns among the sepsis patients in the intensive care unit of Dhaka Medical College Hospital, Bangladesh''. Journal of Molecular Studies and Medicine Research, 02.01.(2017), 80-87.
​
Chicago/Turabian
Khan, A. M., Jannat, F. T. and Ahasan, M. F. ''Antimicrobial sensitivity patterns among the sepsis patients in the intensive care unit of Dhaka Medical College Hospital, Bangladesh''. Journal of Molecular Studies and Medicine Research, 02, no. 01.(2017), 80-87.

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